Priming and signal transduction in neutrophils
| Autor: | Peter A. Ward, Blair A.M. Walker |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Neutrophils
Neutrophile Phosphatidic Acids Receptor upregulation In Vitro Techniques Diglycerides Cellular and Molecular Neuroscience Developmental Neuroscience Superoxides Humans Platelet Activating Factor Receptors Immunologic Protein Kinase C Chemistry Degranulation food and beverages Receptors Formyl Peptide Cell biology N-Formylmethionine Leucyl-Phenylalanine Neurology Immunology Second messenger system Calcium Signal transduction Priming (psychology) Signal Transduction |
| Zdroj: | Biological signals. 1(5) |
| ISSN: | 1016-0922 |
| Popis: | The priming response is a common feature for almost all agents which activate neutrophils. The priming response is associated with a number of events such as degranulation, receptor upregulation, increases in [Ca2+]i and the production of lipid second messengers. For each of these associated events there are data to suggest that priming can also occur in their absence. These contradictions suggest that either the true mechanism for priming has not been found or that there are multiple pathways by which the primed state can be reached. The latter is more likely to be the case. |
| Databáze: | OpenAIRE |
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