Kaposi Sarcoma in HIV Infected Patients
| Autor: | Adriana Hristea, Eliza Manea, Oana Săndulescu, Otilia Elisabeta Benea, Serban Benea, Raluca Jipa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
business.industry
virus diseases hiv medicine.disease Virology late presenters 03 medical and health sciences kaposi disease 0302 clinical medicine 030220 oncology & carcinogenesis Hiv infected patients Medicine 030212 general & internal medicine Sarcoma General Pharmacology Toxicology and Pharmaceutics business General Dentistry |
| Zdroj: | Acta Medica Marisiensis, Vol 62, Iss 2, Pp 285-288 (2016) |
| ISSN: | 2247-6113 |
| Popis: | Objective: The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS). Methods: We retrospectively studied data on HIV-infected patients hospitalized in one tertiary care hospital in Bucharest, Romania, in whom Kaposi Sarcoma was diagnosed, between January 2008 and November 2013. Results: We identified 27 HIV-infected patients diagnosed with KS within 6 years. They had a median age of 42 years old and a median CD4 cell count of 101 cells per mm3 at the time of KS diagnosis. All patients received antiretroviral therapy (ART), with 18 patients (66%) already on ART at the time of KS diagnosis. Most patients (59%) were classified as ACTG poor-risk and 56% as Mitsuyasu stage I. The overall prognosis was poor, with 41% mortality, in a median time span of 6 months, significantly correlated with gastrointestinal involvement (p=0.019), poor-risk KS in ACTG classification (p Conclusion: KS remains an important cause of morbidity and mortality in patients with HIV infection, especially in late presenters. |
| Databáze: | OpenAIRE |
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