Self-administered faecal occult blood tests do not increase compliance with screening for colorectal cancer: results of a randomized controlled trial
| Autor: | J Kettner, J Verne, Andrew Farmer, N Mortenson, David Mant, J. M. A. Northover |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Epidemiology Colorectal cancer Population Rectum Sensitivity and Specificity law.invention Sex Factors Randomized controlled trial law Internal medicine medicine Humans Mass Screening education Mass screening Aged education.field_of_study business.industry Rectal Neoplasms Public Health Environmental and Occupational Health Age Factors Faecal occult blood Middle Aged medicine.disease Surgery Diet Clinical trial medicine.anatomical_structure Oncology Occult Blood Colonic Neoplasms Patient Compliance Self-Examination Test performance Female Reagent Kits Diagnostic business |
| Popis: | In the UK, compliance with conventional faecal occult blood (FOB) tests such as Haemoccult is about 50% in the general population. It has been postulated that characteristics of the performance of conventional tests, in particular the need for dextrous gathering and manipulation of faeces, delay in receiving results, and the recommended dietary restrictions, may all diminish compliance. New FOB tests have been developed, popularly termed 'magic toilet paper' tests, which not only minimize faecal manipulation but are also self-reported. Compliance rates with two self-administered faecal occult blood tests (Early Detector and Coloscreen Self-Test) were compared with Haemoccult in a randomized trial involving 1,842 subjects aged 40-74 years. Use of self-administered FOB tests did not increase compliance significantly, with rates of 52.1% for Early Detector, 50.6% for Coloscreen and 49.1% for Haemoccult. Moreover, dietary restriction did not reduce compliance significantly (restricted 49.3%, unrestricted 51.8%). A wide variation (from 1.3% to 21.4%) in positivity rates was observed which was dependent on which of the three tests was used and whether dietary restrictions were applied. Since the physical aspects of test performance do not appear to determine an individual's decision to be screened, self-administered tests will not overcome the problem of poor compliance with FOB screening. |
| Databáze: | OpenAIRE |
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