Dry eye disease: A longitudinal study among pregnant women in Enugu, south east, Nigeria
| Autor: | Nwachukwu Nkiru Z, Onwubiko Stella, Nnemma N. Udeh, Agu Polycarp U, Nwachukwu Daniel C, Eegwui Ifeoma R |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Longitudinal study Nigeria Disease 03 medical and health sciences 0302 clinical medicine Pregnancy Surveys and Questionnaires medicine South east Prevalence Schirmer's test Humans Ocular Surface Disease Index Prospective Studies 030219 obstetrics & reproductive medicine medicine.diagnostic_test Obstetrics business.industry Repeated measures design medicine.disease Pregnancy Complications Ophthalmology 030221 ophthalmology & optometry Dry Eye Syndromes Female Analysis of variance business Follow-Up Studies |
| Zdroj: | The ocular surface. 17(3) |
| ISSN: | 1937-5913 |
| Popis: | The objective of this study was to determine the course and prevalence of dry eye disease (DED) across different trimesters among pregnant women in Enugu, South East, Nigeria.A prospective longitudinal study design was used. Pregnant women attending the antenatal clinic of the University of Nigeria Teaching Hospital, Enugu, were consecutively recruited in their second trimester for the study. DED was assessed subjectively using the Ocular Surface Disease Index (OSDI) and objectively using Tear Break-up Time (TBUT) and Schirmer's test. These tests were performed during the second and third trimesters and six weeks post-partum. Data were analyzed using the Statistical Package for Social Sciences version 20 and repeated measures analysis of variance (ANOVA) was used to compare the means of the different parameters.A total of 134 pregnant women participated in the study. The mean age of the women was 30.8 (±5.5) years. There were significant decreases (p 0.05) in TBUT and Schirmer's values in the third trimester compared to the second trimester and the post-partum period. The highest score on the OSDI (18.6 ± 6.8) was obtained in the third trimester. The presence of DED was determined using cut-offs for TBUT10 s or Schirmer's test10 mm and the OSDI ≥13. Both symptoms of OSDI and prevalence of DED increased significantly (p 0.05) from the second to the third trimester but returned to their lowest values 6 weeks post-partum.The prevalence of DED was highest in the third trimester and lowest 6 weeks post-partum. |
| Databáze: | OpenAIRE |
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