Risk Factors for Venous Thromboembolism in Patients With Small Cell Lung Cancer
Autor: | Konstantinos Livanios, Ioannis Vathiotis, Elias Kotteas, Evangelos Dimakakos, Konstantinos N. Syrigos, Ioannis Gkiozos, Georgia Gomatou, Elias Kainis |
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Rok vydání: | 2021 |
Předmět: |
Male
Cancer Research medicine.medical_specialty Lung Neoplasms Body Mass Index Metastasis Risk Factors Internal medicine medicine Humans In patient cardiovascular diseases Stage (cooking) Aged Retrospective Studies Lung business.industry Incidence (epidemiology) Anticoagulants Venous Thromboembolism General Medicine Middle Aged equipment and supplies medicine.disease Small Cell Lung Carcinoma medicine.anatomical_structure Oncology Female Non small cell business Complication Venous thromboembolism |
Zdroj: | Anticancer Research. 41:1523-1528 |
ISSN: | 1791-7530 0250-7005 |
Popis: | Background/aim Small cell lung cancer (SCLC) accounts for 13% of all lung cancers. Venous thromboembolism (VTE) is a frequent complication. The purpose of this study was to investigate the incidence and risk factors for VTE in SCLC patients. Patients and methods Retrospective analysis of patients with histologically confirmed SCLC treated between January 2015 and June 2018 at Sotiria General Hospital, Athens, Greece. Results Two hundred and seventeen patients were included in the analysis. The incidence of VTE was 4.1%. Increased body mass index (BMI) was correlated with the development of VTE. Moreover, VTE appeared more frequently in patients with major vessel infiltration and with poor Eastern Cooperative Oncology Group Performance Status. Other factors, including gender, age, stage, presence of metastasis, treatment, immobilization, anticoagulation, comorbidities, and laboratory values did not correlate with the development of VTE. Conclusion Factors associated with the development of VTE were BMI, major vessel infiltration and PS. Identifying factors that predispose to VTE could help physicians detect high-risk patients who would benefit from prophylactic anticoagulation therapy. |
Databáze: | OpenAIRE |
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