Shark mouth pancreaticojejunostomy reduced the rate of clinically related pancreatic fistula: a historic cohort comparative analysis
| Autor: | Chunhui Yuan, Mu-xing Li, Zhaolai Ma, Bin Jiang, Hangyan Wang, Li Zhang, Lei Li, Dianrong Xiu |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Mouth
medicine.medical_specialty Hepatology business.industry Incidence (epidemiology) Gastroenterology Anastomosis medicine.disease Pancreaticoduodenectomy Surgery Pancreatic Fistula Postoperative Complications Risk Factors Pancreatic fistula Pancreaticojejunostomy Propensity score matching Cohort Sharks medicine Animals Humans business Sensitivity analyses Pancreatic stump Retrospective Studies |
| Zdroj: | HPB. 24:727-736 |
| ISSN: | 1365-182X |
| DOI: | 10.1016/j.hpb.2021.09.023 |
| Popis: | Background A novel procedure called shark mouth pancreaticojejunostomy (SMP) was developed, for the reconstruction of the pancreatic stump which has a theoretical advantage for anastomosis healing and wide applicability. Methods A comparative study of the patients who underwent SMP (SMP cohort) and those who underwent end-to-end dunking pancreaticojejunostomy (historic cohort) at Peking University Third Hospital was conducted. Each group was analyzed for the incidence of clinically relevant postoperative pancreatic fistula (CR-POPF) and morbidities. Results The clinicopathological data of 151 patients from the SMP cohort and 82 patients from the historic cohort were analyzed. In the SMP group, the rate of CR-POPF was 7.3% (11/151), which was significantly lower than the rate of CR-POPF in the historic group as 19.5% (16/82) (P = 0.005). The primary results were unaffected by sensitivity analyses based on several risk factors for CR-POPF. The rates of morbidities besides CR-POPF were 15.9% (24/151) in the SMP group and 17.1% (14/82) in the historic cohort (P = 0.194). The principal results were not changed by the propensity score matched (PSM) analysis. Conclusion SMP is a safe and simple surgical procedure for the reconstruction of the pancreatic stump compared with end-to-end dunking pancreticojejunostomy. |
| Databáze: | OpenAIRE |
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