Effect of Film Dressing on Acute Radiation Dermatitis Secondary to Proton Beam Therapy
| Autor: | Takeshi Arimura, Yuya Toi, Takashi Ogino, Shinichi Nagayama, Takashi Yoshiura, Yoshio Hishikawa, Kiyotaka Wada, Ikuko Chuman, Naoaki Kondo, Michiko Kawabata |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Cancer Research Every other day medicine.medical_specialty medicine.medical_treatment Administration Cutaneous 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Proton Therapy Humans Radiology Nuclear Medicine and imaging Surgical Tape Adverse effect Proton therapy Aged Aged 80 and over Radiation business.industry Prostatic Neoplasms Middle Aged Bandages Surgery Radiation therapy Oncology 030220 oncology & carcinogenesis Acute radiation dermatitis Acute Disease Radiodermatitis business Surgical tape |
| Zdroj: | International journal of radiation oncology, biology, physics. 95(1) |
| ISSN: | 1879-355X |
| Popis: | Acute radiation dermatitis (ARD) is one of the most common adverse events of proton beam therapy (PBT), and there is currently no effective method to manage ARD. The purpose of this study was to examine the prophylactic effect of a film dressing using Airwall on PBT-induced ARD compared with standard skin managements.A total of 271 patients with prostate cancer who were scheduled for PBT at our center were divided into 2 groups based on their own requests: 145 patients (53%) chose Airwall (group A) and 126 patients (47%) received standard treatments (group B). We evaluated irradiated skin every other day during PBT and followed up once a week for a month after completion of PBT.Grade 0, 1, 2, and 3 dermatitis were seen in 2, 122, 21, and 0 and 0, 65, 57, and 4 patients in groups A and B, respectively (P.001). Numbers of days to grades 1 and 2 ARD development were 34.9 ± 14.3 and 54.7 ± 10.3 and 31.8 ± 11.3 and 54.4 ± 11.6 in groups A and B, respectively. There were no significant differences between the 2 groups. Eighteen patients (12%) in group A who experienced problems in the region covered with Airwall switched to standard skin care after peeling the film off.Film dressing using Airwall reduced the severity of ARD without delaying the response time of the skin to proton beam irradiation compared with standard skin management. Hence, film dressing is considered a promising measure for preventing ARD secondary to PBT. |
| Databáze: | OpenAIRE |
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