Do 'antisense proteins' exist?
| Autor: | Kuo-Chen Chou, David W. Elrod, Chun-Ting Zhang |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Genetics
Base Sequence Databases Factual Molecular Sequence Data Proteins Promoter Computational biology Biology Genetic code Antiparallel (biochemistry) ENCODE Biochemistry DNA Antisense chemistry.chemical_compound chemistry Sense strand Protein Biosynthesis Sense (molecular biology) Codon Terminator Escherichia coli A-DNA Sequence Analysis DNA |
| Zdroj: | Journal of Protein Chemistry. 15:59-61 |
| ISSN: | 1573-4943 0277-8033 |
| Popis: | A DNA double helix consists of two complementary strands antiparallel with each other. One of them is the sense chain, while the other is an antisense chain which does not directly involve the protein-encoding process. The reason that an antisense chain cannot encode for a protein is generally attributed to the lack of certain preconditions such as a promotor and some necessary sequence segments. Suppose it were provided with all these preconditions, could an antisense chain encode for an "antisense protein"? To answer this question, an analysis has been performed based on the existing database. Nine proteins have been found that have a 100% sequence match with the hypothetical antisense proteins derived from the known Escherichia coli antisense chains. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink