A multicentre study:Staphylococcus andEnterococcus susceptibility to antibiotics
| Autor: | G. Satta, S. Cresti, L. M. Greco, G. Ravizzola, T. Ceruti, L. Peroni, E. Pitzus, Adolfo Turano, G. Santini |
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| Rok vydání: | 1994 |
| Předmět: |
Imipenem
Epidemiology Staphylococcus Microbial Sensitivity Tests Microbiology Ampicillin polycyclic compounds medicine Humans Dose-Response Relationship Drug biology Teicoplanin business.industry Glycopeptides Drug Resistance Microbial biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Anti-Bacterial Agents Penicillin Italy Enterococcus bacteria Vancomycin Netilmicin business medicine.drug Piperacillin |
| Zdroj: | European Journal of Epidemiology. 10:567-572 |
| ISSN: | 1573-7284 |
| DOI: | 10.1007/bf01719574 |
| Popis: | A multicentre study to evaluate the susceptibility of Gram-positive cocci isolated from clinical samples, was performed by six centres working in different areas of Italy. We examined 4,544 strains of Staphylococcus aureus, 4,381 strains of coagulase-negative staphylococci and 2,478 strains of enterococci. The following antibiotics were tested: penicillin G, ampicillin, amoxicillin, piperacillin, imipenem, oxacillin, ofloxacin, pefloxacin, ciprofloxacin, gentamicin, tobramycin, amikacin, netilmicin, rifampicin, clindamycin, tetracycline, cotrimoxazole, erythromycin, chloramphenicol, vancomycin and teicoplanin. Oxacillin-susceptible staphylococci confirmed their susceptibility to many other antimicrobial agents while oxacillin-resistant strains confirmed their multiple and frequent resistance to antibiotics. Resistance to oxacillin, cotrimoxazole and chloramphenicol was more frequent in coagulase-negative staphylococci than in Staphylococcus aureus. Aminoglycosides, rifampicin and quinolones were more active against coagulase-negative staphylococci than against Staphylococcus aureus. Enterococci were susceptible to penicillins and imipenem, and moderately susceptible to ciprofloxacin. Susceptibility of 70-79% was observed with high levels of aminoglycosides. Excellent results against staphylococci and enterococci were observed with vancomycin and teicoplanin. |
| Databáze: | OpenAIRE |
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