Accelerated spectroscopic imaging of hyperpolarized C-13 pyruvate using SENSE parallel imaging
| Autor: | Ileana Hancu, David Brandon Whitt, Joseph Edward Piel, Ronald Dean Watkins, Kenneth Fish, Randy Otto John Giaquinto, Arjun Arunachalam |
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| Rok vydání: | 2009 |
| Předmět: |
Physics
Scanner business.industry Preamplifier Spatial encoding Image Enhancement Coil sensitivity Magnetic Resonance Imaging Rats Rats Sprague-Dawley Optics Nuclear magnetic resonance Electromagnetic coil Pyruvic Acid Animals Humans Molecular Medicine Radiology Nuclear Medicine and imaging Carbon Radioisotopes Hyperpolarization (physics) Parallel imaging business Algorithms Spectroscopy Chemical shift imaging |
| Zdroj: | NMR in Biomedicine. 22:867-873 |
| ISSN: | 1099-1492 0952-3480 |
| DOI: | 10.1002/nbm.1401 |
| Popis: | The ability to accelerate the spatial encoding process during a chemical shift imaging (CSI) scan of hyperpolarized compounds is demonstrated through parallel imaging. A hardware setup designed to simultaneously acquire 13C data from multiple receivers is presented here. A system consisting of four preamplifiers, four gain stages, a transmit coil, and a four receive channel rat coil was built for single channel excitation and simultaneous multi-channel detection of 13C signals. The hardware setup was integrated with commercial scanner electronics, allowing the system to function similar to a conventional proton multi-channel setup, except at a different frequency. The ability to perform parallel imaging is demonstrated in vivo. CSI data from the accelerated scans are reconstructed using a self-calibrated multi-spectral parallel imaging algorithm, by using lower resolution coil sensitivity maps obtained from the central region of k-space. The advantages and disadvantages of parallel imaging in the context of imaging hyperpolarized compounds are discussed. Copyright © 2009 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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