High viral frequency in children with gastroesophageal reflux-related chronic respiratory disorders
| Autor: | Marina Saetta, Cinzia Giacometti, Marta Vadori, Graziella Turato, Fiorella Calabrese, Stefania Rizzo, Angelo Barbato, Deborah Snijders, Francesca Lunardi, Marialuisa Valente, C. Panizzolo |
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| Rok vydání: | 2008 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Esophageal pH Monitoring Rhinovirus Respiratory Tract Diseases medicine.disease_cause Serology Pathogenesis medicine Humans Respiratory system Lung medicine.diagnostic_test business.industry Hydrogen-Ion Concentration Respiratory Syncytial Viruses medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Immunology Chronic Disease Gastroesophageal Reflux Female Viral disease business Esophageal pH monitoring Bronchoalveolar Lavage Fluid Respiratory tract |
| Zdroj: | Pediatric pulmonology. 43(7) |
| ISSN: | 1099-0496 |
| Popis: | Introduction In the pediatric population chronic respiratory disorders (CRDs) include many pathological entities in which gastroesophageal reflux (GER) may play a role in the induction or persistence of clinical symptoms. It is not well established whether infective agents may be present in lung aspiration. The aim of the work was to investigate whether different infective agents could be found in children with GER-related CRDs. Materials and Methods Extensive microbiological investigations including culture for bacterial agents, serology, direct fluorescent antigen and polymerase chain reaction analyses for different respiratory viruses were performed in 32 children (18 males, 14 females, mean age 5.0 ± 2.4 years). Fifteen children out of 32 considered as “aspirators” (lipid-laden macrophage index—LLMI—≥86 and pathological pH-assay) were compared to 17 “non-aspirators” (LLMI |
| Databáze: | OpenAIRE |
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