Preliminary studies of analgesic and anti-inflammatory properties of Caesalpinia ferrea crude extract
| Autor: | JoséC.T. Carvalho, S J Sarti, JoséR.M. Teixeira, Jairo Kenupp Bastos, Pergentino José Cunha Souza, David dos Santos Filho |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.drug_class Analgesic Administration Oral Pain Pharmacognosy Carrageenan Anti-inflammatory Excipients Mice Acetic acid chemistry.chemical_compound Oral administration Drug Discovery Animals Edema Medicine Rats Wistar Caesalpinia Acetic Acid Pharmacology Analgesics Plants Medicinal Dose-Response Relationship Drug biology Traditional medicine Plant Extracts business.industry biology.organism_classification Rats Disease Models Animal chemistry Female Libidibia ferrea business Injections Intraperitoneal |
| Zdroj: | Journal of Ethnopharmacology. 53:175-178 |
| ISSN: | 0378-8741 |
| DOI: | 10.1016/0378-8741(96)01441-9 |
| Popis: | The crude aqueous extract of the fruits of Caesalpinia ferrea Mart. (Leguminosae) has been investigated for possible anti-inflammatory and analgesic properties. The carrageenan induced rat hind paw edema was significantly inhibited (P < 0.05) by oral administration of 300 mg/kg of this extract. A centrally mediated analgesic effect was not observed, however, there was a dose dependent reduction in the number of total writhes induced by acetic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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