Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis
| Autor: | Mark S. Humayun, Pei-An Lo, Kyana Huang, Lan Yue, Qifa Zhou |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
retina
lcsh:Mechanical engineering and machinery medicine.medical_treatment Review 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Medicine lcsh:TJ1-1570 Electrical and Electronic Engineering Neurostimulation 030304 developmental biology 0303 health sciences Retina ultrasound business.industry Mechanical Engineering Ultrasound Retinal Neuromodulation (medicine) medicine.anatomical_structure Visual cortex chemistry Control and Systems Engineering Retinal Prosthesis neuromodulation Ultrasonic sensor business Neuroscience 030217 neurology & neurosurgery neurostimulation visual restoration |
| Zdroj: | Micromachines, Vol 11, Iss 929, p 929 (2020) Micromachines |
| ISSN: | 2072-666X |
| Popis: | Ultrasound is an emerging method for non-invasive neuromodulation. Studies in the past have demonstrated that ultrasound can reversibly activate and inhibit neural activities in the brain. Recent research shows the possibility of using ultrasound ranging from 0.5 to 43 MHz in acoustic frequency to activate the retinal neurons without causing detectable damages to the cells. This review recapitulates pilot studies that explored retinal responses to the ultrasound exposure, discusses the advantages and limitations of the ultrasonic stimulation, and offers an overview of engineering perspectives in developing an acoustic retinal prosthesis. For comparison, this article also presents studies in the ultrasonic stimulation of the visual cortex. Despite that, the summarized research is still in an early stage; ultrasonic retinal stimulation appears to be a viable technology that exhibits enormous therapeutic potential for non-invasive vision restoration. |
| Databáze: | OpenAIRE |
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