Human brain ages with hierarchy-selective attenuation of prediction errors
| Autor: | Yi Fang Hsu, Florian Waszak, Juho Strömmer, Jarmo A. Hämäläinen |
|---|---|
| Přispěvatelé: | National Taiwan Normal University (NTNU), Centre Neurosciences intégratives et Cognition (INCC - UMR 8002), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), University of Jyväskylä (JYU) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Mismatch negativity Audiology Electroencephalography Random Allocation [SCCO]Cognitive science Cognition 0302 clinical medicine prediction errors EEG electroencephalography (EEG) predictive coding media_common Aged 80 and over medicine.diagnostic_test AcademicSubjects/SCI01870 05 social sciences Brain Middle Aged havaintopsykologia auditory perception Evoked Potentials Auditory Original Article Female Psychology Adult Auditory perception medicine.medical_specialty Cognitive Neuroscience media_common.quotation_subject Sensory system kuulohavainnot 050105 experimental psychology Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience P3a Perception P3b medicine Humans 0501 psychology and cognitive sciences AcademicSubjects/MED00385 Aged Working memory [SCCO.NEUR]Cognitive science/Neuroscience aging havainnot ikääntyminen Acoustic Stimulation AcademicSubjects/MED00310 Psychomotor Performance 030217 neurology & neurosurgery Forecasting |
| Zdroj: | Cerebral Cortex Cerebral Cortex, Oxford University Press (OUP), 2021, 31 (4), pp.2156-2168. ⟨10.1093/cercor/bhaa352⟩ Cerebral Cortex, Oxford University Press (OUP), 2020, ⟨10.1093/cercor/bhaa352⟩ Cerebral Cortex (New York, NY) |
| ISSN: | 1047-3211 1460-2199 |
| DOI: | 10.1093/cercor/bhaa352⟩ |
| Popis: | From the perspective of predictive coding, our brain embodies a hierarchical generative model to realize perception, which proactively predicts the statistical structure of sensory inputs. How are these predictive processes modified as we age? Recent research suggested that aging leads to decreased weighting of sensory inputs and increased reliance on predictions. Here we investigated whether this age-related shift from sensorium to predictions occurs at all levels of hierarchical message passing. We recorded the electroencephalography responses with an auditory local–global paradigm in a cohort of 108 healthy participants from 3 groups: seniors, adults, and adolescents. The detection of local deviancy seems largely preserved in older individuals at earlier latency (including the mismatch negativity followed by the P3a but not the reorienting negativity). In contrast, the detection of global deviancy is clearly compromised in older individuals, as they showed worse task performance and attenuated P3b. Our findings demonstrate that older brains show little decline in sensory (i.e., first-order) prediction errors but significant diminution in contextual (i.e., second-order) prediction errors. Age-related deficient maintenance of auditory information in working memory might affect whether and how lower-level prediction errors propagate to the higher level. |
| Databáze: | OpenAIRE |
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