Role of transrectal ultrasound guided salvage cryosurgery for recurrent prostate carcinoma after radiotherapy
| Autor: | John C. Saliken, Bryan Donnelly, M Rose, B Weber, John W. Robinson, D S Ernst, P M A Brasher, John C. Rewcastle |
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| Rok vydání: | 2005 |
| Předmět: |
Gadolinium DTPA
Male Biochemical recurrence Cancer Research medicine.medical_specialty Time Factors Urology medicine.medical_treatment Brachytherapy Contrast Media Salvage therapy Cryosurgery Models Biological Prostate cancer Erectile Dysfunction Recurrence medicine Humans Prospective Studies External beam radiotherapy Aged Ultrasonography Salvage Therapy Radiotherapy business.industry Prostate Prostatic Neoplasms Middle Aged Prostate-Specific Antigen medicine.disease Magnetic Resonance Imaging Surgery Radiation therapy Oncology Cryotherapy Neoplasm Recurrence Local Recurrent Prostate Carcinoma business Follow-Up Studies |
| Zdroj: | Prostate Cancer and Prostatic Diseases. 8:235-242 |
| ISSN: | 1476-5608 1365-7852 |
| DOI: | 10.1038/sj.pcan.4500811 |
| Popis: | Despite improvements in treatment of localized prostate cancer, local recurrence remains a significant problem. A total of 46 patients with proven local cancer recurrence following external beam radiotherapy entered a prospective clinical trial using ultrasound-guided cryosurgery to ablate the residual prostate gland. Persistent complications included one urethra-rectal fistula, incontinence (2), retention (3), and treatment induced erectile dysfunction (7). Using the PSA definitions for biochemical failure as PSA>or=0.3 ng/ml, the Kaplan-Meier plots showed the incidence of patients to be free of biochemical recurrence at 51 and 44% at 1 and 2 y, respectively. For a PSA>or=1.0, the values at 1 and 2 y were 72 and 58%. |
| Databáze: | OpenAIRE |
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