Helicobacter pylori status and endoscopy follow-up of patients having a history of perforated duodenal ulcer
| Autor: | John Wong, Ka-Fai Kwok, FJ Branicki, Simon Law, Peter H. M. Tung, Kent-Man Chu, Henry H. Tuen |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Perforation (oil well) Rapid urease test Epigastric pain Gastroenterology Endoscopy Gastrointestinal Helicobacter Infections Peptic Ulcer Perforation Recurrence Internal medicine Biopsy medicine Humans Radiology Nuclear Medicine and imaging Aged Aged 80 and over biology medicine.diagnostic_test Helicobacter pylori business.industry Middle Aged biology.organism_classification Endoscopy Surgery medicine.anatomical_structure Logistic Models Duodenal Ulcer Multivariate Analysis Duodenum Female business Follow-Up Studies |
| Zdroj: | Gastrointestinal endoscopy. 50(1) |
| ISSN: | 0016-5107 |
| Popis: | Background: The aim of this study was to determine whether the recurrence of symptoms or ulcer disease in patients with a history of perforated duodenal ulcer is related to Helicobacter pylori infection. Methods: One hundred sixty-three consecutive patients with history of perforated duodenal ulcer unrelated to nonsteroidal anti-inflammatory drugs underwent upper endoscopy. Any recurrent symptoms or complications were documented. Regardless of the endoscopic findings, three antral biopsy specimens were taken for histologic examination and a rapid urease test. Results: There was a preponderance of men (male/female = 5.3:1). The mean age was 55.9 years. Sixty-seven (41.1%) patients gave a history of recurrent epigastric pain, seven of whom also had a history of bleeding ulcer. Upper endoscopy was performed at a mean of 74.5 ± 7.1 months after operation. Positive endoscopic findings were noted in 68 (41.7%) patients; H pylori was found in the biopsy specimens from 77 (47.2%) patients. Recurrent duodenal ulcer was found in 29 (17.8%) patients and was significantly related to male gender, recurrent epigastric pain, bleeding ulcer, longer interval from previous operation, and positive H pylori status. Positive H pylori status and male gender were independent factors associated with recurrent duodenal ulcer. Conclusions: Recurrent ulcer disease in patients with a history of perforated duodenal ulcer is related to H pylori infection. (Gastrointest Endosc 1999;50:58-62.) |
| Databáze: | OpenAIRE |
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