A CASE OF INTERLEUKIN-12 RECEPTOR β-1 DEFICIENCY WITH RECURRENT LEISHMANIASIS
| Autor: | Ozden Sanal, Leman Yel, Fatma Gumruk, Gülten Seçmeer, Fügen Ersoy, Gulten Turkkani, Ilhan Tezcan, Ateş Kara |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Microbiology (medical) Antiprotozoal Agents Salmonella infection Anti-Infective Agents Ciprofloxacin Recurrence Amphotericin B medicine Humans Genetic Predisposition to Disease Receptor Interleukin 12 receptor beta 1 subunit business.industry Receptors Interleukin-12 Interleukin Leishmaniasis medicine.disease Infectious Diseases Visceral leishmaniasis Child Preschool Salmonella Infections Pediatrics Perinatology and Child Health Immunology Interleukin 12 Leishmaniasis Visceral business medicine.drug |
| Zdroj: | Pediatric Infectious Disease Journal. 26:366-368 |
| ISSN: | 0891-3668 |
| Popis: | Interleukin-12 receptor beta-1 (IL-12Rbeta1) defect is generally associated with selective susceptibility to weakly pathogenic mycobacteria and Salmonella species. Patients rarely experience infections caused by other organisms. We report a 5-year-old patient with IL-12Rbeta1 deficiency who developed recurrent visceral leishmaniasis 6 months apart. The patient responded to lyposomal amphotericin B treatment reasonably well. |
| Databáze: | OpenAIRE |
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