Analytics of Quinine and its Derivatives
| Autor: | Mariusz Kluska, Wiesław Prukała, Anna Marciniuk-Kluska, Dorota Prukała |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Green chemistry
Quinidine Quinine Chromatography 010405 organic chemistry 010401 analytical chemistry Green Chemistry Technology 01 natural sciences High-performance liquid chromatography 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound Capillary electrophoresis chemistry parasitic diseases medicine Isotachophoresis Cinchonidine medicine.drug |
| Zdroj: | Critical Reviews in Analytical Chemistry. 46:139-145 |
| ISSN: | 1547-6510 1040-8347 |
| DOI: | 10.1080/10408347.2014.996700 |
| Popis: | The objective of this study was to perform a synthesis and analysis of the most important information on quinine and its derivatives, which are still very important in the treatment of malaria. The analysis of stereoisomers of quinine and its derivatives was conducted using two techniques, high-performance liquid chromatography and capillary electrophoresis. Particularly noteworthy is the technique used for the determination of isotachophoresis, referred to as one of the so-called green chemistry techniques. Particular attention was paid to properties and the use of quinine and its derivatives in the treatment of malaria. The analytical part will supplement knowledge about quinidine, quinine, and cinchonidine, and will contribute to the growth of research on the so-much-needed drugs against malaria. |
| Databáze: | OpenAIRE |
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