The association of brachial artery diameter with noncalcified coronary plaque burden in apparently healthy individuals

Autor: Taryn F. Moy, Elliot K. Fishman, Lisa R. Yanek, Diane M. Becker, Dhananjay Vaidya, Lewis C. Becker, Brian G. Kral
Rok vydání: 2013
Předmět:
Zdroj: Coronary Artery Disease. 24:657-662
ISSN: 0954-6928
DOI: 10.1097/mca.0000000000000034
Popis: OBJECTIVE Coronary atherosclerosis has been associated with systemic arterial remodeling even in nonatherosclerotic vessels. However, it is not known whether systemic remodeling is differentially associated with the cumulative atherosclerotic process, reflected by putatively quiescent calcified plaque (CP), or with active atherosclerosis, consisting of noncalcified plaque (NCP). We thus examined the association of brachial artery diameter (BAD), an artery that does not suffer clinical atherosclerosis, with the presence and the extent of coronary CP and NCP. METHODS We studied 688 apparently healthy, asymptomatic participants from 350 families with a history of early-onset coronary artery disease (
Databáze: OpenAIRE