Clinical and histologic assessment of lateral alveolar ridge augmentation using a synthetic long-term bioabsorbable membrane and an allograft
Autor: | Philip J. Vassilopoulos, Robert S. Kellar, Marjorie K. Jeffcoat, Tae Heon Kang, Nicolaas C. Geurs, Michael S. Reddy, Jonathan Korostoff |
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Rok vydání: | 2008 |
Předmět: |
Adult
Male Barrier membrane Biopsy Dentistry Bone Matrix Absorption Dioxanes Osteogenesis Absorbable Implants Surgical Wound Dehiscence Alveolar ridge Alveolar Process Humans Surgical Wound Infection Transplantation Homologous Longitudinal Studies Bone regeneration Aged Dental Implants Bone Transplantation Chemistry business.industry Demineralized bone matrix Soft tissue Membranes Artificial Alveolar Ridge Augmentation Middle Aged Guided Tissue Regeneration Periodontal Periodontics Crest Female Implant business Polyglycolic Acid Biomedical engineering Follow-Up Studies |
Zdroj: | Journal of periodontology. 79(7) |
ISSN: | 0022-3492 |
Popis: | Background: Guided bone regeneration (GBR) is a widely used procedure for augmenting alveolar ridge width prior to placement of endosseous implants. Various graft materials and barrier membranes (non-resorbable and bioabsorbable) have been used in GBR. The aim of this study was to assess the performance of a new bioabsorbable, synthetic polyglycolic acid/trimethylene carbonate (PGA/TMC) barrier membrane with an increased absorption time in conjunction with a combination of assayed demineralized bone matrix and cortical cancellous chips uniformly dispersed in a thermoplastic biologic carrier. Methods: At 72 potential implant sites in 38 subjects, ridge width at the crest and 4 mm apical to the crest was measured before and 6 months after a GBR procedure using the long-term (LT) PGA/TMC membrane and an allograft in a thermoplastic carrier. Before placement of endosseous implants, 48 biopsy specimens were obtained from the augmentation sites and analyzed histomorphometrically. Results: The GBR procedure increased the mean ridge width at the crest from 2.4 to 5.2 mm. This 216% change from baseline was significant (P |
Databáze: | OpenAIRE |
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