Supplementary Figure 2 from Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example

Autor: C. Norman Coleman, Mansoor M. Ahmed, Jayne M. Stommel, Matthew F. Brown, Emanuel F. Petricoin, Mariaelena Pierobon, Lance Liotta, Barbara H. Rath, Sanjeewani T. Palayoor, Veit Sandfort, Molykutty J. Aryankalayil, Adeola Y. Makinde, Iris Eke
Rok vydání: 2023
DOI: 10.1158/1535-7163.22505059.v1
Popis: Gene expression of mTOR/AKT related genes after single dose and multifractionated radiation. DU145 human prostate carcinoma cells were irradiated with 10 Gy single dose (SD) or 5 fractions of 2 Gy or 10 fractions of 1 Gy (2 Gy a day) as multifractionated (MF) radiotherapy. At indicated time points after radiation, cells were lysed and RNA was isolated.
Databáze: OpenAIRE