Relationship between mean platelet volume elevation and left ventricular mass index in hypertensive patients
| Autor: | Necati Dagli, Murat Özgüler, Hasan Korkmaz, Ali Gürel, Mustafa Yavuzkir, Mücahid Yılmaz, Tolga Çakmak, Orhan Dogdu, Ertugrul Kurtoglu, Ayhan Uysal, Mehmet Akbulut |
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| Rok vydání: | 2014 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Blood Pressure Newly diagnosed Biochemistry Left ventricular mass Internal medicine Healthy control Humans Medicine Platelet activation Stage (cooking) Mean platelet volume Aged Ultrasonography Hematology business.industry Biochemistry (medical) Cell Biology General Medicine Middle Aged Platelet Activation Cross-Sectional Studies Case-Control Studies Hypertension Cardiology Female Hypertrophy Left Ventricular Observational study business Mean Platelet Volume |
| Zdroj: | Journal of International Medical Research. 42:781-787 |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/0300060513517486 |
| Popis: | Objectives: To compare the mean platelet volume (MPV; a general marker of platelet activation) in groups of patients with and without hypertension and to analyse its relationship with left ventricular mass index (LVMI). Methods: This cross-sectional, observational study enrolled newly diagnosed patients with untreated stage I–II hypertension and healthy control subjects without hypertension. MPV was measured using a haematology analyser. Echocardiography was performed on all of the study participants. Results: A total of 50 newly diagnosed patients with hypertension and 50 healthy control subjects were enrolled in the study. The majority of the demographic characteristics and laboratory findings were not significantly different between the two groups. The mean ± SD MPV was significantly higher in the hypertensive group compared with the control group (10.3 ± 1.4 fl versus 9.2 ± 1.8 fl, respectively). The mean ± SD LVMI was significantly higher in the hypertensive group compared with the control group (115.9 ± 23.0 g/m2 versus 95.7 ± 23.4 g/m2, respectively). There was no significant correlation between MPV and LVMI. Conclusion: In patients with untreated hypertension, despite elevated MPV levels there was no correlation between LVMI and MPV. |
| Databáze: | OpenAIRE |
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