Clinical and therapeutic features of acute cholecystitis in diabetic patients
| Autor: | Andra Maria Trotea, Gabriel Catalin Smarandache, Valeriu Ardeleanu, Dan Sabau, Ana Maria Dascalu, Cristinel Dumitru Badiu, Bogdan Socea, Cristian Balalau, Dragos Serban, Radu Iulian Spataru, Simona Andreea Balasescu, Catalin Alius, Ion G. Motofei, Alexandru Dan Sabau |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Surgical wound Retrospective cohort study Articles General Medicine medicine.disease Comorbidity Immunology and Microbiology (miscellaneous) Diabetes mellitus Internal medicine medicine Cholecystitis Cholecystectomy Liver function tests business Glycemic |
| Zdroj: | Exp Ther Med |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2021.10190 |
| Popis: | The present study aimed to compare the clinical, paraclinical, intraoperative findings, and postoperative complications in acute cholecystitis in diabetic patients vs. non-diabetic patients. A 2-year retrospective study was performed on the patients who underwent emergency cholecystectomy for acute cholecystitis between 2017 and 2019 at the 4th Department of Surgery, Emergency University Hospital Bucharest. The diabetic subgroup numbered 46 eligible patients and the non-diabetic one 287 patients. Demographics, the severity of the clinical forms, biological variables (including white cell count, urea, creatinine, coagulation and liver function tests) comorbidity status, surgical approach, postoperative complications, and hospital stay were analyzed. Statistical analyses were performed to assess comparative results between the aforementioned data (SPSS V 13.0). The CCI and ASA risk classes were increased in the diabetic group, with 34.78% of patients having 3 or more associated comorbidities. No statistically significant associations were demonstrated between diabetes and the severity of the cholecystitis and risk for conversion. Postoperatively both minor complications such as surgical site infections and major cardiovascular events were more common in the diabetic subgroup (P=0.0254), well associated with the preoperative status and baseline cardiovascular comorbidities. Laparoscopic cholecystectomy is a safe procedure for diabetic patients, which can provide the best outcomes, by decreasing the risks of surgical wounds. Attentive perioperative care and good glycemic control must be provided to minimize the risk of complications. |
| Databáze: | OpenAIRE |
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