Multicenter Evaluation of Prehospital Seizure Management in Children

Autor: Manish I. Shah, Chelsea Stanford, Daniel G Ostermayer, John M. Carey, Nicole Fumo, Jonathan R. Studnek, E. Brooke Lerner, Lorin R. Browne
Rok vydání: 2020
Předmět:
Zdroj: Prehospital Emergency Care. 25:475-486
ISSN: 1545-0066
1090-3127
DOI: 10.1080/10903127.2020.1788194
Popis: Seizures are a common reason why emergency medical services (EMS) transports children by ambulance. Timely seizure cessation prevents neurologic morbidity, respiratory compromise, and mortality. Implementing recommendations from an evidence-based pediatric prehospital guideline may enhance timeliness of seizure cessation and optimize medication dosing.We compared management of pediatric prehospital seizures across several EMS systems after protocol revision consistent with an evidence-based guideline.Using a retrospective, cross-sectional approach, we evaluated actively seizing patients (0-17 years old) EMS transported to a hospital before and after modifying local protocols to include evidence-based recommendations for seizure management in three EMS agencies. We electronically queried and manually abstracted both EMS and hospital data at each site to obtain information about patient demographics, medications given, seizure cessation and recurrence, airway interventions, access obtained, and timeliness of care. The primary outcome of the study was the appropriate administration of midazolam based on route and dose. We analyzed these secondary outcomes: frequency of seizure activity upon emergency department (ED) arrival, frequency of respiratory failure, and timeliness of care.We analyzed data for 533 actively seizing patients. Paramedics were more likely to administer at least one dose of midazolam after the protocol updates [127/208 (61%) vs. 232/325 (71%),Implementation of an evidence-based seizure protocol for EMS increased midazolam administration. Patients frequently received an incorrect weight-based dose. Future research should focus on optimizing administration of the correct dose of midazolam to improve seizure cessation.
Databáze: OpenAIRE