Trajectory in obsessive-compulsive disorder comorbidities
Autor: | Carlos Alberto de Bragança Pereira, Victor Fossaluza, Maria Alice de Mathis, Maria Conceição do Rosário, James F. Leckman, Roseli G. Shavitt, Euripedes Constantino Miguel, Ana Gabriela Hounie, Juliana Belo Diniz, Ygor Arzeno Ferrão |
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Rok vydání: | 2013 |
Předmět: |
Adult
Male Obsessive-Compulsive Disorder medicine.medical_specialty Comorbidity behavioral disciplines and activities Risk Factors Obsessive compulsive mental disorders medicine Humans Pharmacology (medical) Age of Onset Psychiatry Biological Psychiatry Depression (differential diagnoses) INFERÊNCIA ESTATÍSTICA Psychiatric Status Rating Scales Pharmacology Mental Disorders Separation anxiety disorder Clinical course Bayes Theorem medicine.disease humanities Substance abuse Psychiatry and Mental health Neurology Disease Progression Anxiety Female Neurology (clinical) Age of onset medicine.symptom Psychology Brazil Clinical psychology |
Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
ISSN: | 0924-977X |
Popis: | The main goal of this study is to contribute to the understanding of the trajectory of comorbid disorders associated with obsessive-compulsive disorder (OCD) according to the first manifested psychiatric disorder and its impact in the clinical course of OCD and subsequent psychiatric comorbidities. One thousand and one OCD patients were evaluated at a single time point. Standardized instruments were used to determine the current and lifetime psychiatric diagnoses (Structured Clinical Interview for DSM-IV Axis I and for impulse-control disorders) as well as to establish current obsessive-compulsive, depressive and anxiety symptom severity (Yale-Brown Obsessive-Compulsive Scale; Dimensional Yale-Brown Obsessive-Compulsive Scale, Beck Depression and Anxiety Inventories and the OCD Natural History Questionnaire). To analyze the distribution of comorbidities according to age at onset Bayesian approach was used. Five hundred eight patients had the first OC symptom onset till the age of 10 years old. The first comorbidity to appear in the majority of the sample was separation anxiety disorder (17.5%, n=175), followed by ADHD (5.0%, n=50) and tic disorders (4.4%, n=44). OCD patients that presented with separation anxiety disorder as first diagnosis had higher lifetime frequency of post-traumatic stress disorder (p=0.003), higher scores in the Sexual/Religious dimension (p=0.04), Beck Anxiety (p |
Databáze: | OpenAIRE |
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