Pneumococcal serotype 19F conjugate vaccine induces cross-protective immunity to serotype 19A in a murine pneumococcal pneumonia model

Autor:	Ingileif Jonsdottir, Sigurveig T. Sigurdardottir, Håvard Jakobsen, Dominique Schulz, Viktor D. Sigurdsson
Rok vydání:	2003
Předmět:	Serotype Immunology Cross immunity Active immunization Microbiology Pneumococcal conjugate vaccine Pneumococcal Vaccines Mice Conjugate vaccine Medicine Animals Humans Serotyping Vaccines Conjugate business.industry Vaccination Immunization Passive Infant biochemical phenomena metabolism and nutrition Pneumonia Pneumococcal medicine.disease Virology Antibodies Bacterial Infectious Diseases Streptococcus pneumoniae Immunization Pneumococcal pneumonia Microbial Immunity and Vaccines bacteria Parasitology business medicine.drug
Zdroj:	Infection and immunity. 71(5)
ISSN:	0019-9567
Popis:	Immunization with a pneumococcal conjugate vaccine (PNC) containing serotype 19F induces cross-reactive antibodies to 19A in mice and human infants. Active immunization with PNC and passive immunization with serum samples from infants vaccinated with PNC containing serotype 19F, but not serotype 19A, protected against lung infection caused by both serotypes in a murine model.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9c4810456e46feedc351e0e3e475b8 https://pubmed.ncbi.nlm.nih.gov/12704178 Zobrazit plný text záznamu