Relationship of Post-Transplant Lymphoproliferative Disorders (PTLD) Subtypes and Clinical Outcome in Pediatric Heart Transplant Recipients: A Retrospective Single Institutional Analysis/Experience of 558 Patients

Autor:	Yan Liu, Billy C. Wang, Craig W. Zuppan, Peter Chau, James Fitts, Richard Chinnock, Jun Wang
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Pediatric Cancer Research Transplantation Lymphoma Oncology and Carcinogenesis post-transplant CMV lymphoma Hematology Organ Transplantation Cardiovascular survival Rare Diseases Oncology Clinical Research EBV lymphoproliferative disorder Hodgkin's Disease heart transplant Cancer
Zdroj:	Cancers Volume 15 Issue 3 Pages: 976 Cancers, vol 15, iss 3
ISSN:	2072-6694
DOI:	10.3390/cancers15030976
Popis:	Post-transplant lymphoproliferative disorders (PTLD) are heterogenous lymphoproliferative disorders that develop as a consequence of immunosuppression in transplant recipients. We sought to determine if subtypes of PTLD correlated with different outcomes. We performed a retrospective review of PTLD occurring in pediatric heart transplant recipients. A total of 558 children and infants underwent cardiac transplantation at our institution between 1985 and 2019 and were followed until March 2021. Forty-nine of 558 patients developed PTLD (8.8%). As compared to older children (>one year of age), infant recipients (
Databáze:	OpenAIRE
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