The acceptability, feasibility, and possible benefits of a neurobiologically-informed 5-day multifamily treatment for adults with anorexia nervosa
| Autor: | Jason McCray, Walter H. Kaye, Ivan Eisler, Stephanie Knatz Peck, Laura Hill, Christina E. Wierenga, Amber Scott, Laura Greathouse, Danika Peterson |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 050103 clinical psychology medicine.medical_specialty Anorexia Nervosa media_common.quotation_subject medicine.medical_treatment Disease law.invention Young Adult 03 medical and health sciences 0302 clinical medicine Neurobiology Randomized controlled trial law Intervention (counseling) medicine Psychoeducation Humans 0501 psychology and cognitive sciences Attrition media_common business.industry 05 social sciences medicine.disease 030227 psychiatry Psychiatry and Mental health Treatment Outcome Anorexia nervosa (differential diagnoses) Physical therapy Female Temperament business Psychopathology |
| Zdroj: | International Journal of Eating Disorders. 51:863-869 |
| ISSN: | 0276-3478 |
| DOI: | 10.1002/eat.22876 |
| Popis: | Objective Novel treatments for adults with anorexia nervosa (AN) are lacking. Recent scientific advances have identified neurobiologically-driven temperament contributors to AN symptoms that may guide development of more effective treatments. This preliminary study evaluates the acceptability, feasibility and possible benefits of a multicenter open trial of an intensive 5-day neurobiologically-informed multifamily treatment for adults with AN and their supports (SU). The temperament-focused treatment combines psychoeducation of AN neurobiology and SU involvement to develop skills to manage traits contributing to disease chronicity. Method Fifty-four adults with AN and at least one SU (n = 73) received the 5-day treatment. Acceptability, feasibility, and attrition were measured post-treatment. Clinical outcome (BMI, eating disorder psychopathology, family function) was assessed post-treatment and at >3-month follow-up. Results The treatment had low attrition, with only one drop-out. Patients and SU rated the intervention as highly acceptable, and clinicians reported good feasibility. At post-treatment, patients demonstrated significantly increased BMI, reduced eating disorder psychopathology, and improved family function. Benefits were maintained in the 39 patients who completed follow-up assessment, with 62% reporting full or partial remission. Discussion Preliminary results are promising and suggest this novel treatment is feasible and acceptable. To establish treatment efficacy, fully-powered randomized controlled trials are necessary. |
| Databáze: | OpenAIRE |
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