Treatment of Hypertension With an Implantable Electronic Device
| Autor: | C. Walton Lillehei, Bilgutay Am |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
medicine.medical_specialty
Hypertension Renal Baroreceptor Arteriosclerosis medicine.medical_treatment Electric Stimulation Therapy Pressoreceptors Stimulation Kidney Essential hypertension Splanchnic nerves Dogs Internal medicine medicine Animals business.industry Research musculoskeletal neural and ocular physiology Carotid sinus General Medicine medicine.disease Carotid Sinus medicine.anatomical_structure Endocrinology Blood pressure Equipment and Supplies nervous system Electrotherapy Hypertension cardiovascular system Cardiology Electronics business circulatory and respiratory physiology |
| Zdroj: | JAMA: The Journal of the American Medical Association. 191:649 |
| ISSN: | 0098-7484 |
| Popis: | In some 90% to 95% of patients, the development of hypertension cannot be attributed to a definable cause.1One theory of the etiology of at least some forms of "essential hypertension" which has received experimental support is that of altered systemic pressure regulation by the "resetting" of the baroreceptor mechanisms.2-4 Kubicek et al2demonstrated experimentally the mechanism of resetting by showing a systemic blood-pressure rise within 20 hours of continuous electrical stimulation of the splanchnic nerves and observing that pulse rates were normal, indicating that baroreceptor mechanisms were no longer attempting to compensate. As stimulation was stopped, blood pressure fell and pulse rate increased, indicating that the baroreceptor mechanisms had been "reset" at higher levels and were acting to oppose pressure fall. McCubbin4showed that while the regulatory mechanism of the carotid sinus is active in both normotensive and hypertensive dogs, the baroreceptors of renal hypertensive |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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