Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds

Autor:	Syuzanna R. Harutyunyan, Ricard Solà, Beatriz Maciá, Juan F. Collados
Přispěvatelé:	Synthetic Organic Chemistry
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	DISULFONAMIDE-TI(O-ISO-PR)4-DIALKYL ZINC SYSTEM Grignard reagents 010402 general chemistry DIORGANOZINC REAGENTS 01 natural sciences Catalysis Coupling reaction ORGANOMETALLIC REAGENTS Nucleophile 2-addition reaction Organic chemistry titanium enantioselective catalysis 010405 organic chemistry Chemistry TITANIUM COMPLEXES Enantioselective synthesis TRIALKYLALUMINUM ADDITION General Chemistry carbonyl compound 0104 chemical sciences Enantiopure drug ASYMMETRIC ADDITION Reagent 1 2-addition reaction copper ORGANOMAGNESIUM REAGENTS CROSS-COUPLING REACTIONS ORGANOZINC REAGENTS HIGHLY ENANTIOSELECTIVE ADDITION
Zdroj:	ACS Catalysis, 6(3), 1952-1970. AMER CHEMICAL SOC
ISSN:	2155-5435
Popis:	© 2016 American Chemical Society.Remarkable progress in the enantioselective addition of Grignard reagents to carbonyl compounds has been made over the past decade. This enantioselective transformation now allows the use of these challenging reactive nucleophiles for the formation of chiral alcohols using catalytic amounts of chiral ligands. This review summarizes the developments in this area.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b80d438093f485ee8151e815bbd68dc https://hdl.handle.net/11370/d79fc717-7120-4ff4-ae31-f7d166057132 Zobrazit plný text záznamu