Metabolic effects of cortisol treatment in a marine teleost, the sea raven
| Autor: | Thomas W. Moon, Mathilakath M. Vijayan, T. P. Mommsen, H. C. Glémet |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
biology Physiology Hemitripterus americanus Catabolism Glutamate dehydrogenase Aquatic Science biology.organism_classification Endocrinology Tyrosine aminotransferase Biochemistry Gluconeogenesis Insect Science Internal medicine Glutamine synthetase medicine Animal Science and Zoology Phosphoenolpyruvate carboxykinase Molecular Biology Sea raven hormones hormone substitutes and hormone antagonists Ecology Evolution Behavior and Systematics |
| Zdroj: | The Journal of experimental biology. 199(Pt 7) |
| ISSN: | 1477-9145 |
| Popis: | Sea raven (Hemitripterus americanus) given intraperitoneal implants of coconut oil containing cortisol (50 mg kg−1) and sampled 5 days later had plasma cortisol, glucose and urea concentrations higher than in a sham-implanted group. No differences in plasma ammonia, free amino acid or fatty acid concentrations were apparent between the cortisol-and sham-treated groups. There was no change in hepatic glycogen content, whereas glutamine synthetase, allantoicase, arginase, aspartate aminotransferase, tyrosine aminotransferase, alanine aminotransferase, glutamate dehydrogenase, phosphoenolpyruvate carboxykinase and 3-hydroxyacyl-coenzyme A dehydrogenase activities were higher in the cortisol-treated fish liver compared with the sham-implanted fish. On the basis of these general increases in enzyme activities, our results suggest that cortisol stimulates nitrogen metabolism in the sea raven. Amino acid catabolism may be a major source of substrate for gluconeogenesis and/or oxidation, while fatty acid mobilization may provide the fuel for endogenous use by the liver in cortisol-treated sea raven. These results further support the hypothesis that cortisol plays a role in the regulation of glucose production in stressed fish. |
| Databáze: | OpenAIRE |
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