A longitudinal study of correlations among tardive dyskinesia, drug- induced parkinsonism, and psychosis
Autor: | D. E. Casey, W L Brown, R M Weigel, Hansen Te, William F. Hoffman |
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Rok vydání: | 1992 |
Předmět: |
Adult
Male Dyskinesia Drug-Induced Psychosis Longitudinal study medicine.medical_specialty Psychometrics Dopamine Tardive dyskinesia medicine Cluster Analysis Humans Parkinson Disease Secondary Psychiatry Neurologic Examination Psychiatric Status Rating Scales Models Statistical business.industry Parkinsonism Middle Aged medicine.disease Psychiatry and Mental health Psychotic Disorders Female Neurology (clinical) Drug-induced parkinsonism Partial support business Antipsychotic Agents medicine.drug |
Zdroj: | The Journal of Neuropsychiatry and Clinical Neurosciences. 4:29-35 |
ISSN: | 1545-7222 0895-0172 |
Popis: | Tardive dyskinesia (TD) and drug-induced parkinsonism (DIP) have been hypothesized to reflect opposing states of dopamine (DA) function. In this longitudinal study, 57 psychotic inpatients were rated repeatedly for TD, DIP, and psychosis while receiving neuroleptic medication. Cross-sectional correlations among TD, DIP, and psychosis were weak or nonexistent. Factor and cluster analyses found that 13 patients (23%) were classified into groups characterized by the expected negative correlations. Thus, only partial support was found for the hypothesis that TD and DIP represent opposing states of DA function. |
Databáze: | OpenAIRE |
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