Thalassaemia major and severe left ventricular dysfunction
Autor: | Derek L Connolly, S Handa, M D Sosin, Russell C. Davis |
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Rok vydání: | 2003 |
Předmět: |
Adult
Male Hemolytic anemia medicine.medical_specialty Iron Overload Blood transfusion Heart disease medicine.medical_treatment Miscellanea β thalassaemia Ventricular Dysfunction Left Internal medicine medicine Humans business.industry beta-Thalassemia Transfusion Reaction Beta thalassemia Iron chelation therapy medicine.disease Magnetic Resonance Imaging Dyspnea Endocrinology Hemoglobinopathy Heart failure Cardiology Cardiology and Cardiovascular Medicine business |
Zdroj: | Heart. 89:1162-1162 |
ISSN: | 0007-0769 |
DOI: | 10.1136/heart.89.10.1162 |
Popis: | Patients with β thalassaemia major are dependent upon regular blood transfusions, and consequently are subjected to a large iron load. Accumulation of excess iron leads to heart failure. Iron chelation therapy can delay this process, but compliance is commonly poor. Severe cardiac failure in iron overloaded patients with β thalassaemia major has … |
Databáze: | OpenAIRE |
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