POLYVINYL-PYRROLIDONE-IODINE: AN ASSESSMENT OF ANTIBACTERIAL ACTIVITY
| Autor: | B. A. Saggers, G. T. Stewart |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
Spores
Epidemiology Disinfectant Staphylococcus chemistry.chemical_element Bacillus macromolecular substances Iodine Endospore Microbiology Salmonella Escherichia coli Medicine Povidone-Iodine Candida Skin Clostridium Pharmacology biology Bacteria business.industry Research technology industry and agriculture Fungi Penicillium Povidone Sterilization Streptococcus Articles Sterilization (microbiology) biology.organism_classification Proteus Spore Staining Anti-Bacterial Agents Infectious Diseases Aspergillus chemistry Pseudomonas aeruginosa Polyvinyls Shigella business Antibacterial activity |
| Zdroj: | The Journal of hygiene. 62 |
| ISSN: | 0022-1724 |
| Popis: | Polyvinyl-pyrrolidone-iodine complex (PVP-I) was shown to have a rapid disinfectant activityin vitroagainst vegetative bacteria and fungi and against vegetativeTrichomonas. The presence of organic matter had a slight delaying effect on the killing time. Bacterial spores survived in PVP-I for 17 hr. and fungal spores for 1½ hr. Used as an agent for pre-operative preparation of the skin, PVP-I was more efficient than others tested, rendering the skin surface sterile even when heavily contaminated, and keeping it so for 1 hr. None of the staining characteristics of iodine were noted since PVP-I was easily removed by water. Two individuals, known to be iodine sensitive, developed mild iodism after application of PVP-I.The authors are indebted to the staff of the hospital for their co-operation; and to Berk Pharmaceuticals Limited for supplies of PVP-I, manufactured by them as Betadine (Povidone-iodine B.P.). |
| Databáze: | OpenAIRE |
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