Effect of Soil Properties and Aging Time on Oral and Inhalation Bioaccessibility of Copper Oxide Nanoparticles in Soils

Autor: Yanhua Qiu, Helian Li, Shiwei Li, Fang He, Zongquan Sun, Ming-Hui Chang
Rok vydání: 2021
Předmět:
Zdroj: Bulletin of Environmental Contamination and Toxicology. 107:967-974
ISSN: 1432-0800
0007-4861
Popis: In this study, soils spiked with copper oxide nanoparticles (CuO NPs) or Cu(NO3)2 and aged as long as 90 days were utilized to investigate effect of soil properties and aging on oral and inhalation bioaccessibility of CuO NPs. Results showed that oral bioaccessibility of CuO NPs in gastric phase (GP) ranged from 70% to 84%, it significantly decreased to 50%–70% in intestinal phase (IP). The inhalation bioaccessibility of CuO NPs in artificial lysosomal fluid (ALF) ranged from 66% to 85%, and much higher than that in Gamble’s solution (GS, 3.3%–23%). By comparing CuO NPs to Cu(NO3)2 bioaccessibility, insignificant difference was found. The aging time (D15 and D90) had limited effect on their oral and inhalation bioaccessibility. CEC and free Al were positively and clay content was negatively correlated with CuO NPs inhalation bioaccessibility, while Cu(NO3)2 inhalation bioaccessibility decreased with increasing soil clay content and pH. Our findings provide an essential basis to evaluate the human health risks of CuO NPs.
Databáze: OpenAIRE