Expression of NF-κB and osteopontin of synovial fluid of patients with knee osteoarthritis
| Autor: | Guo-Liang Huang, Yi Shen, Wanchun Wang, Hou-De Zhou, You Chen, Li-Feng Qin, Fang Han, Xin-Zhan Mao, Dan Peng, Li-Hua Qin |
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| Rok vydání: | 2013 |
| Předmět: |
musculoskeletal diseases
Adult Male medicine.medical_specialty Blotting Western Osteoarthritis Nuclear factor κb Gastroenterology Polymerase Chain Reaction Statistics Nonparametric chemistry.chemical_compound stomatognathic system Internal medicine Statistical significance Synovial Fluid medicine Synovial fluid Humans In patient Osteopontin RNA Messenger Aged Medicine(all) biology business.industry Case-control study NF-kappa B NF-κB General Medicine Middle Aged Osteoarthritis Knee medicine.disease chemistry Case-Control Studies biology.protein Female business |
| Zdroj: | Asian Pacific journal of tropical medicine. 6(5) |
| ISSN: | 2352-4146 |
| Popis: | ObjectiveTo explore the significance of osteopontin and nuclear factorκB (NF-κB) expression in patients with knee osteoarthritis.MethodsRT-PCR and enzyme-linked immunosorbent assay were used to measure the Osteopontin (OPN) and NF-κB concentration of knee joint synovial fluid of patients with knee osteoarthritis and trauma fractures, and analyze the relationship between the expressiones of them.ResultsOPN and NF-κB expression at the mRNA and protein levels of patients with knee osteoarthritis were significantly higher than the control group. the result showed statistical significance (P |
| Databáze: | OpenAIRE |
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