Perindopril decreases P wave dispersion in patients with stage 1 hypertension
| Autor: | Azra Meryem Tanrikulu, Nurdan Papila-Topal, Beste Ozben, Ali Serdar Fak, Mutlu Sumerkan, Ahmet Toprak |
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| Přispěvatelé: | Ozben, Beste, Sumerkan, Mutlu, Tanrikulu, Azra Meryem, Papila-Topal, Nurdan, Fak, Ali Serdar, Toprak, Ahmet |
| Rok vydání: | 2009 |
| Předmět: |
P wave dispersion
ANGIOTENSIN-CONVERTING ENZYME Male Medicine (General) medicine.medical_specialty electrocardiography POPULATION-BASED COHORT INHIBITION Angiotensin-Converting Enzyme Inhibitors R5-920 LEFT-VENTRICULAR DYSFUNCTION Endocrinology Internal medicine Atrial Fibrillation Internal Medicine Perindopril medicine Humans In patient Stage (cooking) Aged PAROXYSMAL ATRIAL-FIBRILLATION medicine.diagnostic_test business.industry Atrial fibrillation Middle Aged medicine.disease Blood pressure angiotensin-converting enzyme inhibitor Echocardiography Hypertension RISK-FACTORS Cardiology HEART-FAILURE LOSARTAN SINUS RHYTHM FOLLOW-UP business Body mass index Electrocardiography medicine.drug |
| Zdroj: | Journal of the Renin-Angiotensin-Aldosterone System, Vol 10 (2009) |
| ISSN: | 1470-3203 |
| Popis: | Introduction. Angiotensin-converting enzyme inhibitors prevent atrial fibrillation episodes by effective control of blood pressure and improving electrical and structural remodelling in the atria. Increased P wave dispersion (PWD) is a non-invasive electrocardiographic marker for paroxysmal atrial fibrillation. The aim of the study was to evaluate the effect of perindopril treatment on PWD in hypertensive patients. Methods. Forty-eight hypertensive patients (mean age 57.4±11.8 years, 18 men) were included. Blood pressure values were determined and 12-lead electrocardiograms were recorded at the beginning and at the first week, first month, third month and sixth month of the perindopril treatment.The difference between maximum and minimum P wave durations was calculated as PWD. Results. PWDs were significantly shortened at the first, third and sixth months (41.7±8.8 ms, 39.1±6.9 ms and 38.3±7.1 ms, respectively) compared with baseline and first-week measurements (54.3±9.2 ms and 49.0±9.1 ms, respectively, p Conclusion. Perindopril treatment significantly reduced PWD in hypertensive patients. |
| Databáze: | OpenAIRE |
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