Theta rhythmicity governs human behavior and hippocampal signals during memory-dependent tasks
| Autor: | Juan Linde-Domingo, Frederic Roux, Luca D. Kolibius, Stephanie Gollwitzer, Vijay Sawlani, David T. Rollings, Julia Lifanov, Simon Hanslmayr, Hajo M. Hamer, Johannes Lang, Bernhard P. Staresina, Ramesh Chelvarajah, Marije ter Wal, Maria Wimber |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Periodicity Quantitative Biology::Tissues and Organs Science General Physics and Astronomy Hippocampus Local field potential Hippocampal formation General Biochemistry Genetics and Molecular Biology Article Long-term memory Rhythm Encoding (memory) Reaction Time Humans Theta Rhythm Associative property Multidisciplinary Recall Quantitative Biology::Neurons and Cognition General Chemistry Phase synchronization Magnetic Resonance Imaging Healthy Volunteers Pattern Recognition Visual Mental Recall Female Electrocorticography Cues Psychology Neuroscience |
| Zdroj: | Nature Communications Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| ISSN: | 2041-1723 |
| Popis: | Memory formation and reinstatement are thought to lock to the hippocampal theta rhythm, predicting that encoding and retrieval processes appear rhythmic themselves. Here, we show that rhythmicity can be observed in behavioral responses from memory tasks, where participants indicate, using button presses, the timing of encoding and recall of cue-object associative memories. We find no evidence for rhythmicity in button presses for visual tasks using the same stimuli, or for questions about already retrieved objects. The oscillations for correctly remembered trials center in the slow theta frequency range (1-5 Hz). Using intracranial EEG recordings, we show that the memory task induces temporally extended phase consistency in hippocampal local field potentials at slow theta frequencies, but significantly more for remembered than forgotten trials, providing a potential mechanistic underpinning for the theta oscillations found in behavioral responses. The hippocampus is a central memory hub and exhibits prominent theta oscillations. Here the authors show that oscillations are visible in behavior when decisions depend on memory, paralleled by theta phase synchronization in hippocampal recordings. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink