Molecular motors and the Golgi complex: Staying put and moving through
| Autor: | Kim Brownhill, Laura Wood, Viki Allan |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Molecular Motor Proteins
Endoplasmic reticulum Dynein Golgi Apparatus Microtubule organizing center Cell Biology Golgi apparatus Biology Microtubules Actins Cell biology Motor protein Protein Transport symbols.namesake Microtubule Molecular motor symbols Animals Humans Secretory pathway Developmental Biology |
| Zdroj: | Seminars in Cell & Developmental Biology. 20:784-792 |
| ISSN: | 1084-9521 |
| DOI: | 10.1016/j.semcdb.2009.03.019 |
| Popis: | The Golgi apparatus is a highly dynamic organelle through which nascent proteins released from the endoplasmic reticulum (ER) are trafficked. Proteins are post-translationally modified within the Golgi and subsequently packaged into carriers for transport to a variety of cellular destinations. This transit of proteins, as well as the maintenance of Golgi structure and position, is highly dependent upon the actin and microtubule cytoskeletons and their associated molecular motors. Here we review how motors contribute to the correct functioning of the Golgi in higher eukaryotes and discuss the secretory pathway as a model system for studying cooperation between motor proteins. |
| Databáze: | OpenAIRE |
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