ANTIBODY TO HEPATITIS-B CORE ANTIGEN IN PATIENTS WITH PRIMARY HEPATIC CARCINOMA
| Autor: | Irving Millman, B. S. Blumberg, Anna O'Connell, Gerard Saimot, Maupas P, M. Payet, W. Thomas London, Bernard Larouzé, Barbara G. Werner |
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| Rok vydání: | 1975 |
| Předmět: |
Electrophoresis
Hepatitis B virus Immunodiffusion Antibodies Viral Virus Hepatitis B Antigens Antigen Culture Techniques Carcinoma Medicine Antigens Viral Hepatitis biology business.industry Liver Neoplasms General Medicine Hepatitis B medicine.disease Senegal United States Liver Hepatocellular carcinoma Carrier State Immunology Etiology biology.protein Hong Kong Antibody Liver Extracts business |
| Zdroj: | The Lancet. 306:9-11 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(75)92951-7 |
| Popis: | Antibody to hepatitis-B core antigen (anti-HB c ) was assayed in the serum of patients with primary hepatic carcinoma (P.H.C.) and controls from Hong Kong, West Africa, and the United States. In each region the prevalence of anti-HB c was higher in P.H.C. patients than in controls, ranging from 70 to 95 % in the patients and from 20 to 68% in the controls from Asia and Africa; 24% of P.H.C. patients and 4% of controls from the U.S. had anti-HB c . These data support the hypothesis that chronic infection with hepatitis-B virus is aetiologically related to P.H.C., especially in Asia and Africa, although other factors must also be involved. |
| Databáze: | OpenAIRE |
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