ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer

Autor: Joy Lin, Julie Hong, Armen Gharibi, Daniel Brambilla, Justin Molnar, Malachia Hoover, Yvess Adamian, Jonathan A. Kelber, Laurelin Wolfenden, Sa La Kim
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
lcsh:Medicine
Drug resistance
Chick Embryo
Bioinformatics
Deoxycytidine
Chorioallantoic Membrane
Metastasis
Cell Movement
Transforming Growth Factor beta
Tumor Microenvironment
RNA
Small Interfering
lcsh:Science
Multidisciplinary
biology
Prognosis
3. Good health
Gene Expression Regulation
Neoplastic
Isoenzymes
Biomarker (medicine)
Collagen
Signal transduction
Integrin alpha Chains
Signal Transduction
Antimetabolites
Antineoplastic
Epithelial-Mesenchymal Transition
Integrin
Adenocarcinoma
Aldehyde Dehydrogenase 1 Family
Article
03 medical and health sciences
Downregulation and upregulation
Pancreatic cancer
Cell Line
Tumor
medicine
Biomarkers
Tumor
Animals
Humans
Epithelial–mesenchymal transition
Cell Proliferation
business.industry
lcsh:R
Retinal Dehydrogenase
medicine.disease
Gemcitabine
Pancreatic Neoplasms
030104 developmental biology
Drug Resistance
Neoplasm
Tissue Array Analysis
Cancer research
biology.protein
lcsh:Q
business
Zdroj: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
ISSN: 2045-2322
Popis: Pancreatic ductal adenocarcinoma (PDAC) has single-digit 5-year survival rates at
Databáze: OpenAIRE
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