Novel Synthesis and Characterization of Thiosemicarbazone Compounds Containing 4-Acyl-2-pyrazolin-5-ones

Autor:	Harish R. Dabhi, Arjun K. Rana, Sunil S. Nadkarni, Nayan Ratilal Parekh
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Pyrazolin-5-Ones General Chemistry Carbon-13 NMR Free radical scavenger Medicinal chemistry Metal lcsh:Chemistry chemistry.chemical_compound chemistry lcsh:QD1-999 Elemental analysis visual_art visual_art.visual_art_medium Proton NMR Organic chemistry Semicarbazone Single crystal
Zdroj:	E-Journal of Chemistry, Vol 6, Iss 3, Pp 747-752 (2009)
ISSN:	2090-9810 0973-4945
Popis:	A novel synthesis of 4-acylthiosemicarbazone-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one by condensation of 4-acyl-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one with thiosemicarbazide is carried out. The compounds were characterized on the basis of elemental analysis, IR,1H NMR, Mass, DSC and13C NMR spectral data. The structures were investigated for their antibacterial and antifungal activity. They are very essential to study on cerebral infarction (Free radical scavenger). A single crystal X-ray study of this thiosemicarbazones and their metal complexes is in progress.
Databáze:	OpenAIRE
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