Comment on Helicobacter pylori seroprevalence and the occurrence and severity of psoriasis - Reply
| Autor: | Augusto Diogo Filho, Priscila Miranda Diogo Mesquita, Sônia Antunes de Oliveira Mantese, José Joaquim Rodrigues, Alceu Luiz Camargo Villela Berbert, Miguel Tanús Jorge |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male MEDLINE Enzyme-Linked Immunosorbent Assay Dermatology Severity of Illness Index Helicobacter Infections 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Seroepidemiologic Studies Psoriasis 0502 economics and business Humans Medicine Seroprevalence Letters Helicobacter pylori biology business.industry 05 social sciences Middle Aged medicine.disease biology.organism_classification RL1-803 Case-Control Studies Immunology Female 050211 marketing business |
| Zdroj: | Anais Brasileiros de Dermatologia Anais Brasileiros de Dermatologia, Vol 92, Iss 4, Pp 585-585 (2017) Anais Brasileiros de Dermatologia, Volume: 92, Issue: 4, Pages: 585-585, Published: AUG 2017 |
| ISSN: | 0365-0596 |
| DOI: | 10.1590/abd1806-4841.20177256 |
| Popis: | Psoriasis is a chronic inflammatory disease that affects the skin and joints and has a multifactorial etiology. Recently, it has been suggested that Helicobacter pylori infection may contribute as a trigger for the development of the disease.To determine the prevalence of H. pylori seropositivity in patients with psoriasis and to evaluate the relation between disease severity and H. pylori infection.H. pylori infection was assessed in psoriatic patients and controls by using H. pylori IgG quantitative enzyme immunoassay (ELISA test). The patients were classified according to the severity of the disease (PASI score).One hundred and twenty six patients with psoriasis (73 females and 53 males); mean age 50.48 years; 65 patients (51.59%) had severe psoriasis, 40 (31.75%) moderate psoriasis and 21 (16.67%) mild psoriasis. Twenty one healthy volunteers included as a control group, mean age of 41.05 years, 13 females and 8 males. One hundred and eleven patients with psoriasis tested serologically, 80 (72.07%) were seropositive compared with 7 positive volunteers (33.33%; P=0.002). Forty-nine (75.38%) patients with severe psoriasis were positive, 25 (62.50%) with moderate psoriasis were positive and 6 (28.57%) with mild psoriasis were positive (P=0.045). Study limitations: none.H. pylori infection influences the development of psoriasis and severity of the disease. |
| Databáze: | OpenAIRE |
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