Multilayer vs. global 2D-longitudinal strain in hypertrophic cardiomyopathy
| Autor: | Augustin Coisne, H. Ridon, P. De Groote, A. Duva Pentiah, David Montaigne, A. Coppin, Stéphanie Mouton |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Ejection fraction Longitudinal strain Heart disease business.industry Diastole Hypertrophic cardiomyopathy Retrospective cohort study medicine.disease Sudden cardiac death Internal medicine Heart failure cardiovascular system Cardiology Medicine cardiovascular diseases Cardiology and Cardiovascular Medicine business |
| Zdroj: | Archives of Cardiovascular Diseases Supplements. 10:253-254 |
| ISSN: | 1878-6480 |
| DOI: | 10.1016/j.acvdsp.2018.02.168 |
| Popis: | Introduction Hypertrophic cardiomyopathy (HCM) is a genetic heart disease defined by structural and functional abnormalities of the myocardium. HCM is characterized by systolic and diastolic dysfunction with major complications: sudden cardiac death and terminal heart failure. Altered left ventricular global longitudinal strain (LV GLS) is known to be predictive of these complications. Objective To define whether 2D-longitudinal multilayer strain is of interest on top of LV GLS in HCM. Methods A monocentric retrospective study (2013 to 2017) was conducted on 61 genetically confirmed HCM patients versus 61 matched controls. Transthoracic echocardiography with 2D-LV GLS and multilayer LS analysis (endocardial, mid, epicardial) were performed and a cardiopulmonary exercise testing. Results As expected, LV GLS was significantly decreased in HCM in comparison to controls (respectively −16.8 +/ − 5% vs. −21.7 +/ − 2%, P 0.98; P Conclusion Global and myocardial layers longitudinal strains are altered in HCM, despite supranormal LVEF. Impaired GLS is associated with poor aerobic capacity and predicts severe ventricular rhythmic events. No evidence was found to support strain multilayer analysis on top of GLS. |
| Databáze: | OpenAIRE |
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