Pregnancy and fetal outcomes of chronic hepatitis C mothers with viremia in China

Autor: Calvin Q Pan, Bao-Shen Zhu, Jian-Ping Xu, Jian-Xia Li, Li-Juan Sun, Hong-Xia Tian, Xi-Hong Zhang, Su-Wen Li, Er-Hei Dai
Rok vydání: 2022
Předmět:
Zdroj: World journal of gastroenterology. 28(34)
ISSN: 2219-2840
Popis: Data that assess maternal and infant outcomes in hepatitis C virus (HCV)-infected mothers are limited.To investigate the frequency of complications and the associated risk factors.We performed a cohort study to compare pregnancy and fetal outcomes of HCV-viremic mothers with those of healthy mothers. Risk factors were analyzed with logistic regression.Among 112 consecutive HCV antibody-positive mothers screened, we enrolled 79 viremic mothers. We randomly selected 115 healthy mothers from the birth registry as the control. Compared to healthy mothers, HCV mothers had a significantly higher frequency of anemia [2.6% (3/115)Maternal HCV infections may associate with pregnancy and obstetric complications. We demonstrated a previously unreported association between maternal HCV viremia and a smaller neonatal head circumference, suggesting fetal growth restriction.
Databáze: OpenAIRE