Meiotic studies in a series of 1100 infertile and sterile males

Autor:	Joaquima Navarro, J. Egozcue, S. Marina, Cristina Templado, F. Morer-Fargas, Francesca Vidal
Rok vydání:	1983
Předmět:	Genetics Chromosome Aberrations Male medicine.diagnostic_test urogenital system Testicular biopsy Incidence (epidemiology) Semen Biology Semen analysis medicine.disease Andrology Meiosis Prophase I Testis Chromosome abnormality medicine Humans Metabolic disease Genetics (clinical) Infertility Male
Zdroj:	Human genetics. 65(2)
ISSN:	0340-6717
Popis:	Meiotic studies have been carried out in a series of 1100 infertile and sterile males. Of these, 599 cases have been studied in testicular biopsy, and 501, in semen samples. This is the largest meiotic series published so far. The incidence of meiotic anomalies was 4.3%. The most frequent chromosome abnormality was desynapsis (3.7%). However, the number of cases with a meiotic arrest, usually due (73.9%) to synaptic anomalies in prophase I, was much higher (18.4%). An attempt is made to correlate the incidence of meiotic anomalies with the results of semen analysis. We discuss the prognosis of desynapsis, based on 41 cases studied, and reevaluate the results obtained in semen samples as compared with our previous results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2b2119b64c27a5d325dd7b9b8d1d24 https://pubmed.ncbi.nlm.nih.gov/6654332 Zobrazit plný text záznamu Full text from SpringerLink