In quest of genomic treasure

Autor:	Kimiko Inoue, Atsuo Ogura
Rok vydání:	2015
Předmět:	Genetics Cloning Nuclear Transfer Techniques Genome Mouse Mouse strain Stem Cells Computational biology Biology Embryonic stem cell Mice Genomic reprogramming Animals Animal Science and Zoology Opinions and Hypotheses Treasure Stem cell Nuclear transfer
Zdroj:	The Journal of Reproduction and Development
ISSN:	1348-4400 0916-8818
DOI:	10.1262/jrd.2015-098
Popis:	It should be emphasized that "129" is not simply a number but is also the designation of a mouse strain that has made a great contribution to modern biological science and technology. Embryonic stem cells derived from 129 mice were essential components of gene-targeting strategies in early research. More recently, 129 mice have provided superior donor genomes for cloning by nuclear transfer. Some factor or factors conferring genomic plasticity must exist in the 129 genome, but these remain unidentified.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b240326069cf941f22a16e76d74e935 https://doi.org/10.1262/jrd.2015-098 Zobrazit plný text záznamu