Cashew Gum (Anacardium occidentale) as a Potential Source for the Production of Tocopherol-Loaded Nanoparticles: Formulation, Release Profile and Cytotoxicity
| Autor: | Petr Štěpánek, Hernane S. Barud, Patrícia Severino, Ricardo Luiz Cavalcanti de Albuquerque-Júnior, Eliana B. Souto, Kahynna Cavalcante Loureiro, Marcelo da Costa Mendonça, Juliana Cordeiro Cardoso, Ewa Pavlova, Leandro S. Sangenito, I.B. Lima-Verde, Mônica F. La R. Soares, Alessandro Jäger, Marco Vinícius Chaud, André L.S. Santos |
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| Přispěvatelé: | Universidade do Minho |
| Rok vydání: | 2021 |
| Předmět: |
Technology
Dispersity 02 engineering and technology 01 natural sciences Zeta potential General Materials Science Anacardiaceae Tocopherol Food science Biology (General) Instrumentation Fluid Flow and Transfer Processes biology Chemistry Physics Anacardium General Engineering tocopherol Engineering (General). Civil engineering (General) 021001 nanoscience & nanotechnology Computer Science Applications Drug delivery Nano Technology resin TA1-2040 medicine.symptom 0210 nano-technology Exudate QH301-705.5 QC1-999 Raw material 010402 general chemistry nanoprecipitation medicine Resin QD1-999 Science & Technology Process Chemistry and Technology Cashew gum biology.organism_classification 0104 chemical sciences drug delivery Nanoparticles nanoparticles cashew gum Nanoprecipitation |
| Zdroj: | Applied Sciences, Vol 11, Iss 8467, p 8467 (2021) Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP Applied Sciences Volume 11 Issue 18 |
| ISSN: | 2076-3417 |
| DOI: | 10.3390/app11188467 |
| Popis: | Every year, more than thirty thousand tons of Cashew gum (Anacardium occidentale, family: Anacardiaceae) are produced in Brazil; however, only a small amount is used for different applications in foodstuff and in pharmaceutical industries. As a raw material for the production of drug delivery systems, cashew gum is still regarded as an innovative compound worth to be exploited. In this work, cashew gum was extracted from the crude exudate of cashew tree employing four methodologies resulting in a light brown powder in different yields (40.61% to 58.40%). The total ashes (0.34% to 1.05%) and moisture (12.90% to 14.81%) were also dependent on the purification approach. FTIR spectra showed the typical bands of purified cashew gum samples, confirming their suitability for the development of a pharmaceutical product. Cashew gum nanoparticles were produced by nanoprecipitation resulting in particles of low polydispersity ( This research received funding from the Coordenação Aperfeiçoamento de Pessoal de Nivel Superior (CAPES), Fundação de Ámparo à Pesquisa do Estado de Sergipe (FAPITEC) (PROCESSO: 88887.159533/2017-00 extração, encapsulação e caracterização de bioativos para o interesse biotecnologico) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq 301964/2019-0 Chamada 06/2019, and Chamada CNPq nº 01/2019), from Portuguese Foundation for Science and Technology (FCT/MEC) through national funds, and co-financed by FEDER, under the Partnership Agreement PT2020 for the project UIDB/04469/2020. info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
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