Adenomatous ductal proliferation of the salivary gland
| Autor: | Karl Donath, Guang-Yan Yu |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adenoma
Adult Male Pathology medicine.medical_specialty Adolescent Adenoma Pleomorphic Biology Histogenesis stomatognathic system medicine Acinar cell Humans Salivary Ducts Melanoma General Dentistry Hyperplasia Salivary gland Carcinoma Acinar Cell Secretory Vesicles Cell Differentiation Epithelial Cells Intercalated duct Middle Aged Adenolymphoma medicine.disease Carcinoma Adenoid Cystic Immunohistochemistry Parotid Neoplasms Submandibular Gland Neoplasms medicine.anatomical_structure Otorhinolaryngology Chronic Disease Submandibular Gland Neoplasm Female Surgery Oral Surgery Cell Division Parotitis |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 91:215-221 |
| ISSN: | 1079-2104 |
| Popis: | Objective: The objective of this study is to report a series of patients with adenomatous ductal proliferation of the salivary gland and to investigate the nature and histogenesis of this process. Study Design: The histologic and immunohistochemical studies of 13 patients with adenomatous ductal proliferation of the salivary gland were performed. Results: Ten cases coexisted with other diseases, such as salivary gland tumor or chronic parotitis. Most of the lesions were limited to 1 or 2 lobules and showed prominent ductal proliferation with some acinar cell complexes. The proliferative ducts had a compact growth pattern with little stroma. Dedifferentiation of acinar cells, identified by the loss of their secretory granules and appearing similar to intercalated duct epithelium, was seen in the early stages of adenomatous ductal proliferation. Conclusion: Acinar cells play a role in the histogenesis of salivary gland tumors because acinar cells clearly participate in the formation of the proliferative ducts. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:215-21) |
| Databáze: | OpenAIRE |
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