Volumetric evaluation of CT images of adrenal glands in primary aldosteronism

Autor: Velema, M.S., Canu, L., Dekkers, T., Hermus, A.R.M.M., Timmers, H.J.L.M., Schultze Kool, L.J., Groenewoud, H., Sweep, F.C.G.J., Wilt, G.J. van der, Langenhuijsen, J.F., Lenders, J.W.M., Jacobs, C., Deinum, J.
Přispěvatelé: Public and occupational health, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, APH - Personalized Medicine, APH - Global Health, ACS - Heart failure & arrhythmias
Rok vydání: 2021
Předmět:
Prognostic factor
Adrenal gland neoplasms
Endocrinology
Diabetes and Metabolism
Concordance
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Adrenal Gland Neoplasm
Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13]
X-ray computed
030209 endocrinology & metabolism
Normal values
CT-scanning
Unilateral disease
03 medical and health sciences
0302 clinical medicine
Endocrinology
Primary aldosteronism
Diagnosis
Hyperaldosteronism
medicine
In patient
Tomography
business.industry
Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16]
medicine.disease
Women's cancers Radboud Institute for Health Sciences [Radboudumc 17]
Urological cancers Radboud Institute for Health Sciences [Radboudumc 15]
030220 oncology & carcinogenesis
Nuclear medicine
business
Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
Zdroj: Journal of Endocrinological Investigation, 44, 2359-2366
Journal of endocrinological investigation, 44(11), 2359-2366. Editrice Kurtis s.r.l.
Journal of Endocrinological Investigation, 44, 11, pp. 2359-2366
ISSN: 1720-8386
0391-4097
Popis: Contains fulltext : 244324.pdf (Publisher’s version ) (Open Access) OBJECTIVES: To investigate whether adrenal volumetry provides better agreement with adrenal vein sampling (AVS) than conventional CT for subtyping PA. Furthermore, we evaluated whether the size of this contralateral adrenal was a prognostic factor for clinical outcome after unilateral adrenalectomy. METHODS: We retrospectively analyzed volumes of both adrenal glands of the 180 CT-scans (88/180 with unilateral and 92/180 with bilateral disease) of the patients with PA included in the SPARTACUS trial of which 85 also had undergone an AVS. In addition, we examined CT-scans of 20 healthy individuals to compare adrenal volumes with published normal values. RESULTS: Adrenal volume was higher for the left than the right adrenal (mean and SD: 6.49 ± 2.77 ml versus 5.25 ± 1.87 ml for the right adrenal; p
Databáze: OpenAIRE
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